For optimal antibody effectiveness, sometimes less is more

Christoph Wülfing () and Simon J. Dovedi ()

Nature, 2023, vol. 614, issue 7948, 416-418

Abstract: Antibodies that activate stimulatory or inhibitory receptors are of great therapeutic interest for the treatment of cancer or autoimmune diseases. It emerges that such antibodies work better if they don’t bind to receptors too tightly.

Keywords: Immunology; Medical research (search for similar items in EconPapers)
Date: 2023
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DOI: 10.1038/d41586-023-00244-5

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