X chromosome passed from mother to daughter influences brain ageing

Daniel M. Snell () and James M. A. Turner ()

Nature, 2025, vol. 638, issue 8049, 45-47

Abstract: Older female mice show poor spatial memory when their paternal X chromosome is inactive and only the maternal copy is active. This phenomenon could be responsible for variation in age-related cognitive decline among women.

Keywords: Ageing; Neuroscience; Epigenetics (search for similar items in EconPapers)
Date: 2025
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DOI: 10.1038/d41586-025-00079-2

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