Molecular glue unexpectedly mimics the effect of cancer mutations

Jonathan W. Bushman and Patrick Ryan Potts ()

Nature, 2025, vol. 639, issue 8053, 42-43

Abstract: Many conventional small-molecule drugs work by inhibiting proteins, affecting their function. One small molecule instead imbues a protein with a new function in a mechanism that could inform rational drug design.

Keywords: Drug discovery; Molecular biology; Structural biology; Cancer (search for similar items in EconPapers)
Date: 2025
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/d41586-025-00090-7 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:639:y:2025:i:8053:d:10.1038_d41586-025-00090-7

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/d41586-025-00090-7

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().