Power and sample size calculations for rerandomization

Zach Branson, Inran Li and Peng Ding

Biometrika, 2024, vol. 111, issue 1, 355-363

Abstract: SummaryPower analyses are an important aspect of experimental design, because they help determine how experiments are implemented in practice. It is common to specify a desired level of power and compute the sample size necessary to obtain that power. Such calculations are well known for completely randomized experiments, but there can be many benefits to using other experimental designs. For example, it has recently been established that rerandomization, where subjects are randomized until covariate balance is obtained, increases the precision of causal effect estimators. This work establishes the power of rerandomized treatment-control experiments, thereby allowing for sample size calculators. We find the surprising result that, while power is often greater under rerandomization than complete randomization, the opposite can occur for very small treatment effects. The reason is that inference under rerandomization can be relatively more conservative, in the sense that it can have a lower Type-I error at the same nominal significance level, and this additional conservativeness adversely affects power. This surprising result is due to treatment effect heterogeneity, a quantity often ignored in power analyses. We find that heterogeneity increases power for large effect sizes, but decreases power for small effect sizes.

Keywords: Covariate balance; Design-based inference; Dispersive ordering; Experimental design; Treatment effect heterogeneity (search for similar items in EconPapers)
Date: 2024
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Citations: View citations in EconPapers (2)

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