On the accelerated failure time model for current status and interval censored data
Lu Tian and
Tianxi Cai
Biometrika, 2006, vol. 93, issue 2, 329-342
Abstract:
This paper introduces a novel approach to making inference about the regression parameters in the accelerated failure time model for current status and interval censored data. The estimator is constructed by inverting a Wald-type test for testing a null proportional hazards model. A numerically efficient Markov chain Monte Carlo based resampling method is proposed for obtaining simultaneously the point estimator and a consistent estimator of its variance-covariance matrix. We illustrate our approach with interval censored datasets from two clinical studies. Extensive numerical studies are conducted to evaluate the finite-sample performance of the new estimators. Copyright 2006, Oxford University Press.
Date: 2006
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