A Longitudinal Analysis of the Association Between Long-Term Exposure to Air Pollution and Cognitive Function Among Adults Aged 45 and Older in China

Kai Hu, Jo Mhairi Hale, Hill Kulu, Yang Liu, Katherine Keenan and Jessica Kelley

The Journals of Gerontology: Series B, 2023, vol. 78, issue 3, 556-569

Abstract: ObjectivesEvidence suggests long-term exposure to fine particulate matter air pollution (PM2.5) is associated with a higher risk of cognitive impairment, especially among older adults. This study examines the relationship between PM2.5 exposure and cognitive function in China’s aging population.MethodsWe used longitudinal data from the China Health and Retirement Longitudinal Study (2011–2015) linked with historical PM2.5 concentrations (2000–2015) from remotely sensed satellite data. Growth curve models were applied to estimate associations between PM2.5 exposure (measured in intensity, duration, and a joint variable of intensity with duration for cumulative exposure) and cognitive function.ResultsRelative to the lowest exposure group, exposure in the second group of PM2.5 intensity (35–50 μg/m3) is associated with poorer cognitive function, but higher levels of PM2.5 appear to be associated with better cognitive function, indicating a U-shaped association. Similar patterns are seen for fully adjusted models of PM2.5 duration: the second group (13–60 months) is associated with worse cognitive function than the first group (0–12 months), but coefficients are nonsignificant in longer duration groups. Joint analysis of PM2.5 intensity with duration suggests that duration may play a more detrimental role in cognitive function than intensity. However, we do not find a statistically significant association between PM2.5 exposure and the rate of cognitive decline.DiscussionOur findings are mixed and suggest that some categories of higher and longer exposure to PM2.5 are associated with poorer cognitive function, while that exposures do not hasten cognitive decline. However, more work is necessary to disentangle PM2.5 exposure from individuals’ background characteristics, particularly those jointly associated with cognitive function and urban living.

Keywords: Air pollution; Cognitive function; Cumulative exposure; Health disparities; PM2.5 (search for similar items in EconPapers)
Date: 2023
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The Journals of Gerontology: Series B is currently edited by Psychological Sciences - S. Duke Han, PhD and Social Sciences - Jessica A Kelley, PhD, FGSA

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