 Variation in the dynamics and performance of industrial innovation: what can we learn from vaccines and HIV vaccines?Ohid Yaqub Industrial and Corporate Change, 2018, vol. 27, issue 1, 173-187 Abstract: This article examines contingencies and constraints in problem-solving processes underlying technological change and industry evolution. It shows how learning through practice can help drive technical change but, when this is impeded, the ability to make use of models and engage in experimental learning becomes even more pertinent for explaining variation in the rate and direction of technical change. The article explores HIV as an example of vaccine innovation, and vaccines as an example of medical innovation. I find the absence of these two variables (ability to learn directly in humans, and ability to learn vicariously through animal models) not only make up a large part of how I would characterize “difficulty” in the HIV R&D process, but they also seem to go a long way toward explaining why 33 other diseases have—or have not—had vaccines developed for them. Implications for theory and policy are discussed. JEL-codes: D81 D83 I18 O31 O32 O33 O38 (search for similar items in EconPapers) Downloads: (external link) Related works: Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text Persistent link: https://EconPapers.repec.org/RePEc:oup:indcch:v:27:y:2018:i:1:p:173-187. Ordering information: This journal article can be ordered from Access Statistics for this article Industrial and Corporate Change is currently edited by Josef Chytry More articles in Industrial and Corporate Change from Oxford University Press and the Associazione ICC Oxford University Press, Great Clarendon Street, Oxford OX2 6DP, UK. |
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