Significant sparse polygenic risk scores across 813 traits in UK Biobank

Yosuke Tanigawa, Junyang Qian, Guhan Venkataraman, Johanne Marie Justesen, Ruilin Li, Robert Tibshirani, Trevor Hastie and Manuel A Rivas

PLOS Genetics, 2022, vol. 18, issue 3, 1-21

Abstract: We present a systematic assessment of polygenic risk score (PRS) prediction across more than 1,500 traits using genetic and phenotype data in the UK Biobank. We report 813 sparse PRS models with significant (p

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pgen00:1010105

DOI: 10.1371/journal.pgen.1010105

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