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Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer

Jingxiong Xu, Wei Xu, Jiyeon Choi, Yonathan Brhane, David C Christiani, Jui Kothari, James McKay, John K Field, Michael P A Davies, Geoffrey Liu, Christopher I Amos, Rayjean J Hung and Laurent Briollais

PLOS Genetics, 2023, vol. 19, issue 9, 1-13

Abstract: Common genetic variants associated with lung cancer have been well studied in the past decade. However, only 12.3% heritability has been explained by these variants. In this study, we investigate the contribution of rare variants (RVs) (minor allele frequency

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pgen00:1010902

DOI: 10.1371/journal.pgen.1010902

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