Stability of Patients’ Preferences for Chemotherapy

Sylvia J. T. Jansen, Job Kievit, Marianne A. Nooij and Anne M. Stiggelbout
Additional contact information
Sylvia J. T. Jansen: Department of Clinical Oncology, Department of Medical Decision Making, Leiden University Medical Center, Leiden, the Netherlands
Job Kievit: Department of Medical Decision Making, Leiden University Medical Center, Leiden, the Netherlands
Marianne A. Nooij: Department of Clinical Oncology, Leiden University Medical Center, Leiden, the Netherlands
Anne M. Stiggelbout: Department of Medical Decision Making, Leiden University Medical Center, Leiden, the Netherlands

Medical Decision Making, 2001, vol. 21, issue 4, 295-306

Abstract: Background. Studies have shown that utilities for a particular treatment, elicited by means of a hypothetical treatment scenario, may remain stable within the same patients when examined before, during, and after experiencing that treatment (within-group stability). However, other studies have found that utilities for a particular health state may differ between patient groups who are and who are not experiencing the particular health state (between-group differences). Objective. The authors evaluated this apparent contradiction in the case of adjuvant chemotherapy for breast cancer. A related purpose was to examine whether a chemotherapy scenario adequately reflects the patients’ own experiences with chemotherapy. Method. Forty-three patients with early-stage breast cancer evaluated their actually experienced health state and a chemotherapy scenario before, during, and after undergoing adjuvant chemotherapy (chemotherapy group). A control group of 51 patients for whom chemotherapy was not part of the treatment plan was interviewed at similar points in time. Utilities were elicited by means of a visual analog scale (VAS), a chained time trade-off (TTO), and a chained standard gamble (SG). Results. The utilities for the chemotherapy scenario remained relatively stable over time in the 2 patient groups. Furthermore, the chemotherapy scenario was evaluated more positively by patients in the chemotherapy group than by control patients (e.g., utilities before chemotherapy: VAS 0.69 vs. 0.50, TTO 0.88 vs.0.50, SG 0.92 vs. 0.58, all Ps

Keywords: stability; utility assessment; standard gamble; time trade-off (search for similar items in EconPapers)
Date: 2001
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://journals.sagepub.com/doi/10.1177/0272989X0102100405 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:21:y:2001:i:4:p:295-306

DOI: 10.1177/0272989X0102100405

Access Statistics for this article

More articles in Medical Decision Making
Bibliographic data for series maintained by SAGE Publications ().