A Methodological Framework for Optimally Reorganizing Liver Transplant Regions

James E. Stahl, Nan Kong, Steven M. Shechter, Andrew J. Schaefer and Mark S. Roberts
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James E. Stahl: Department of Radiology & Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston
Nan Kong: Department of Industrial Engineering, University of Pittsburgh, Pennsylvania
Steven M. Shechter: Department of Industrial Engineering, University of Pittsburgh, Pennsylvania
Andrew J. Schaefer: Department of Industrial Engineering, University of Pittsburgh, Pennsylvania, Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania
Mark S. Roberts: Department of Industrial Engineering, University of Pittsburgh, Pennsylvania, Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania

Medical Decision Making, 2005, vol. 25, issue 1, 35-46

Abstract: Background. The United States is divided currently into 11 transplant regions, which vary in area and number of organ procurement organizations (OPOs). Region size affects organ travel time and organ viability at transplant. Purpose. To develop a methodologic framework for determining optimal configurations of regions maximizing transplant allocation efficiency and geographic parity. Methods. An integer program was designed to maximize a weighted combination of 2 objectives: 1) intraregional transplants, 2) geographic parity—maximizing the lowest intraregional transplant rate across all OPOs. Two classes of functions relating liver travel time to liver viability were also examined as part of the sensitivity analyses. Results. Preliminary results indicate that reorganizing regions, while constraining their number to 11, resulted in up to 17 additional transplants/year depending on the travel-viability function; when not constrained, it resulted in up to 18/year of increase. Conclusion. Our analysis indicates that liver transplantation may benefit through region reorganization. The analytic method developed here should be applicable to other organs and sets of organs.

Keywords: transplant regions; organ procurement organizations; liver transplants (search for similar items in EconPapers)
Date: 2005
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Citations: View citations in EconPapers (13)

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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:25:y:2005:i:1:p:35-46

DOI: 10.1177/0272989X04273137

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