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A Randomized Controlled Trial of a Decision Aid for Women at Increased Risk of Ovarian Cancer

K. Tiller, B. Meiser, C. Gaff, J. Kirk, T. Dudding, K.-A. Phillips, M. Friedlander and K. Tucker
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K. Tiller: Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia; Department of Psychology, Macquarie University, Sydney, Australia; Prince of Wales Clinical School, University of NSW, Sydney, Australia
B. Meiser: Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia; Prince of Wales Clinical School, University of NSW, Sydney, Australia
C. Gaff: Genetic Health Services, Victoria, Australia; Familial Cancer Center, Royal Melbourne Hospital, Melbourne, Australia
J. Kirk: Familial Cancer Service, Westmead Hospital, Sydney, Australia
T. Dudding: Hunter Family Cancer Service, Hunter Genetics, and the University of Newcastle, Australia
K.-A. Phillips: Division of Hematology and Medical Oncology, Peter MacCallum Cancer Institute, Melbourne, Australia
K. Tucker: Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia; Prince of Wales Clinical School, University of NSW, Sydney, Australia

Medical Decision Making, 2006, vol. 26, issue 4, 360-372

Abstract: Purpose . To carry out a randomized controlled trial of a decision aid for women at increased risk of developing ovarian cancer to facilitate decision making regarding risk management options. Methods . This randomized trial, conducted through 6 familial cancer centers, compared the efficacy of tailored decision aid to that of a general educational pamphlet in preparing women for decision making. Participants . 131 women with a family history of breast and/or ovarian cancer or of hereditary nonpolyposis colorectal cancer. Outcome measures . Decisional conflict, knowledge about ovarian cancer risk management options, and psychological adjustment were reassessed at 3 time points. Results . Compared to those who received the pamphlet (control), women who received the decision aid (intervention) were significantly more likely to report a high degree of acceptability of the educational material at both follow-up assessment time points. Findings indicate neither group experienced significant increases in psychological distress at either follow-up assessment time points relative to baseline. Two weeks postintervention, the intervention group demonstrated a significant decrease in decisional conflict compared to the control group (t = 2.4, P

Keywords: risk management; hereditary ovarian cancer; decision aid; randomized controlled trial (search for similar items in EconPapers)
Date: 2006
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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:26:y:2006:i:4:p:360-372

DOI: 10.1177/0272989X06290486

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