Relative Influence of Antibiotic Therapy Attributes on Physician Choice in Treating Acute Uncomplicated Pyelonephritis

Jessina C. McGregor, Anthony D. Harris, Jon P. Furuno, Douglas D. Bradham and Eli N. Perencevich
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Jessina C. McGregor: Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, mcgregoj@ohsu.edu
Anthony D. Harris: Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore
Jon P. Furuno: Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore
Douglas D. Bradham: Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, VA Maryland Healthcare System, Baltimore
Eli N. Perencevich: Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, VA Maryland Healthcare System, Baltimore

Medical Decision Making, 2007, vol. 27, issue 4, 387-394

Abstract: Background. Reducing excess duration of antibiotic therapy is a strategy for limiting the spread of antibiotic resistance, but altering physician practice to accomplish this requires knowledge of the factors that influence physician antibiotic choice. The authors aimed to quantify physician willingness to trade between 4 attributes of antibiotic therapies: different therapy durations, failure rates, dosing frequencies, and days of diarrhea as a side effect when treating acute uncomplicated pyelonephritis. Methods. The authors distributed conjoint analysis questionnaires to physicians enrolling patients in a randomized trial comparing 2 antibiotics in pyelonephritis treatment. For each question, respondents were required to select 1 of 2 antibiotics based on the values of the 4 attributes. Proportional hazards regression was used to model predictors of physician choice. Results. Eighty-seven of 88 physicians completed the questionnaire. Duration of therapy, days of diarrhea, and failure rate were significant predictors of choice (P

Keywords: Key words: decision making; pyelonephritis; urinary tract infection; choice behavior; antibacterial agents/administration and dosage; questionnaires. (Med Decis Making 2007; 27: 387—394) (search for similar items in EconPapers)
Date: 2007
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:27:y:2007:i:4:p:387-394

DOI: 10.1177/0272989X07302556

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