A Review and Meta-Analysis of Utility Values for Lung Cancer

Julie Sturza
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Julie Sturza: Office of Policy, Economics and Innovation, US Environmental Protection Agency, Washington, DC, sturza.julie@epa.gov

Medical Decision Making, 2010, vol. 30, issue 6, 685-693

Abstract: Background. Published utility estimates for lung cancer are plentiful and vary greatly. The reason for this variability is unclear, but may result from differences in the methods used to elicit each utility. Purpose. To identify a set of pooled lung cancer utility estimates reflective of the available literature and determine which methodological factors significantly influence the value of lung cancer utility. Data Sources. Searches of PubMed, the NHS Economic Evaluation Database, and the Cost Effectiveness Analysis Registry from the Center for the Evaluation of Value and Risk in Health. Study Selection. English-language studies were included if they presented at least one previously unpublished lung cancer utility value, noted the elicitation technique and utility value provider. Data Extraction and Analysis. Two trained readers independently reviewed each article and extracted information for analysis. A hierarchical linear model (HLM) was used to perform a meta-regression with cancer stage, lower bound of scale, upper bound of scale, respondent, elicitation method, and lung cancer subtype as explanatory variables. Data Synthesis. Twenty-three articles containing 223 unique utility values were included. Lung cancer stage and subtype, the upper bound label of the utility scale, and respondent identity were significant predictors of utility (P

Keywords: cost utility analysis; randomized trial methodology; risk stratification; population-based studies; scale development/validation. (search for similar items in EconPapers)
Date: 2010
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Citations: View citations in EconPapers (6)

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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:30:y:2010:i:6:p:685-693

DOI: 10.1177/0272989X10369004

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