Use of a Catalytic Model to Estimate Hepatitis A Incidence in a Low-Endemicity Country

Ba’ Pham, Maggie Hong Chen, Andrea C. Tricco, Andrea Anonychuk, Murray Krahn and Chris T. Bauch

Medical Decision Making, 2012, vol. 32, issue 1, 167-175

Abstract: Background . Evaluating the cost-effectiveness of vaccine programs with dynamic modeling requires accurate estimates of incidence over time. Because infectious diseases are often underreported, supplementary data and statistical analyses are required to estimate true incidence. This study estimates the true incidence of hepatitis A virus (HAV) infection in Canada using a catalytic model. Methods . A catalytic model was used to reconcile HAV seroprevalence data with the corresponding true cumulative risk of infection estimated from incidence data. Results . The average annual reported incidence was 6.2 cases per 100 000 from 1980 to 1989 and 7.7/100 000 from 1990 to 1999, indicating that Canada is a low-incidence country. The seroprevalence in Canadian-born individuals (n = 7 studies) was approximately 1%−8% in ages

Keywords: hepatitis A; prevalence; incidence; decision support techniques (search for similar items in EconPapers)
Date: 2012
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.sagepub.com/doi/10.1177/0272989X11398489 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:32:y:2012:i:1:p:167-175

DOI: 10.1177/0272989X11398489

Access Statistics for this article

More articles in Medical Decision Making
Bibliographic data for series maintained by SAGE Publications ().