Health Care Costs for State Transition Models in Prostate Cancer

Murray D. Krahn, Karen E. Bremner, Brandon Zagorski, Shabbir M. H. Alibhai, Wendong Chen, George Tomlinson, Nicholas Mitsakakis and Gary Naglie

Medical Decision Making, 2014, vol. 34, issue 3, 366-378

Abstract: Objective . To obtain estimates of direct health care costs for prostate cancer (PC) from diagnosis to death to inform state transition models. Methods . A stratified random sample of PC patients residing in 3 geographically diverse regions of Ontario, Canada, and diagnosed in 1993–1994, 1997–1998, and 2001–2002, was selected from the Ontario Cancer Registry. We retrieved patients’ pathology reports to identify referring physicians and contacted surviving patients and next of kin of deceased patients for informed consent. We reviewed clinic charts to obtain data required to allocate each patient’s observation time to 11 PC-specific health states. We linked these data to health care administrative databases to calculate resource use and costs (Canadian dollars, 2008) per health state. A multivariable mixed-effects model determined predictors of costs. Results . The final sample numbered 829 patients. In the regression model, total direct costs increased with age, comorbidity, and Gleason score (all P

Keywords: prostate cancer; costs; economic evaluation (search for similar items in EconPapers)
Date: 2014
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:34:y:2014:i:3:p:366-378

DOI: 10.1177/0272989X13493970

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