A Review and Meta-analysis of Colorectal Cancer Utilities

Sandjar Djalalov, Linda Rabeneck, George Tomlinson, Karen E. Bremner, Robert Hilsden and Jeffrey Hoch

Medical Decision Making, 2014, vol. 34, issue 6, 809-818

Abstract: Objective. To perform a systematic review of utility weights for colorectal cancer (CRC) health states reported in the scientific literature and to determine the effects of disease factors, patient characteristics, and utility methods on utility values. Methods. We identified 26 articles written in English and published from January 1980 to January 2013, providing 351 unique utilities for CRC health states elicited from 6546 unique respondents. The CRC utility data were analyzed using linear mixed-effects models with CRC type, stage, time to or from initial care, utility measurement instrument, and administration method as independent variables. Results. In the base case model, the estimated utility for a patient with stage I to III CRC more than 1 year after surgery, rated using a self-administered time tradeoff instrument, was 0.90. Stage, time to or from initial care, and utility measurement instrument were associated with statistically significant utility differences ranging from −0.19 to 0.02. Utilities for patients with stage IV cancer were 0.19 lower (P

Keywords: colorectal cancer; quality of life; preferences; utility assessment; meta-analysis (search for similar items in EconPapers)
Date: 2014
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Citations: View citations in EconPapers (5)

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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:34:y:2014:i:6:p:809-818

DOI: 10.1177/0272989X14536779

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