Catalog and Comparison of Societal Preferences (Utilities) for Lung Cancer Health States

Angela C. Tramontano, Deborah L. Schrag, Jennifer K. Malin, Melecia C. Miller, Jane C. Weeks, J. Shannon Swan and Pamela M. McMahon

Medical Decision Making, 2015, vol. 35, issue 3, 371-387

Abstract: Background. The EQ-5D and SF-6D are 2 health-related quality-of-life indexes that provide preference-weighted measures for use in cost-effectiveness analyses. Methods. The National Cancer Institute’s Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium included the EQ-5D and SF-12v2 in their survey of newly diagnosed lung cancer patients. Utilities were calculated from patient-provided scores for each domain of the EQ-5D or the SF-6D. Utilities were calculated for categories of cancer type, stage, and treatment. Results. There were 5015 enrolled lung cancer patients with a baseline survey in CanCORS; 2396 (47.8%) completed the EQ-5D, and 2344 (46.7%) also completed the SF-12v2. The mean (standard deviation) utility from the EQ-5D was 0.78 (0.18), and from the SF-6D (derived from SF-12v2) was 0.68 (0.14). The EQ-5D demonstrated a ceiling effect, with 20% of patients reporting perfect scores, translating to a utility of 1.0. No substantial SF-6D floor effects were noted. Utilities increased with age and decreased with stage and comorbidities. Patient-reported (EQ-5D) visual analog scale scores for health status had a moderate ( r = 0.48, p

Keywords: lung cancer; utilities; quality-of-life; EQ5D; SF6D (search for similar items in EconPapers)
Date: 2015
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Citations: View citations in EconPapers (2)

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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:35:y:2015:i:3:p:371-387

DOI: 10.1177/0272989X15570364

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