Valuation Survey of EQ-5D-Y Based on the International Common Protocol: Development of a Value Set in Japan

Takeru Shiroiwa, Shunya Ikeda, Shinichi Noto, Takashi Fukuda and Elly Stolk
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Takeru Shiroiwa: Center for Outcomes Research and Economic Evaluation for Health (C2H), National Institute of Public Health, Wako, Saitama, Japan
Shunya Ikeda: Department of Medicine, International University of Health and Welfare, Narita, Chiba, Japan
Shinichi Noto: Department of Health Sciences, Niigata University of Health and Welfare, Niigata, Japan
Takashi Fukuda: Center for Outcomes Research and Economic Evaluation for Health (C2H), National Institute of Public Health, Wako, Saitama, Japan
Elly Stolk: EuroQol Research Foundation, Rotterdam, South Holland, The Netherlands

Medical Decision Making, 2021, vol. 41, issue 5, 597-606

Abstract: Background EQ-5D-Y is a preference-based measure for children and adolescents (aged 8–15 y). This is the first study to develop an EQ-5D-Y value set for converting EQ-5D-Y responses to index values. Methods We recruited 1047 respondents (aged 20–79 y) from the general population, stratified by gender and age group, in 5 Japanese cities. All data were collected through face-to-face surveys. Respondents were asked to value EQ-5D-Y states for a hypothetical 10-y-old child from a proxy perspective using composite time tradeoff (cTTO) and a discrete choice experiment (DCE). The discrete choice data were analyzed using a mixed logit model. Latent DCE values were then converted to a 0 (death)/1 (full health) scale by mapping them to the cTTO values. Results The mean observed cTTO value of the worst health state [33333] was 0.20. Analysis of the DCE data showed that the coefficients of the domains related to mental functions (“Having pain or discomfort†and “Feeling worried, sad, or unhappy†) were larger than those for the domains related to physical and social functions. By converting latent DCE values to a utility scale, we constructed a value set for EQ-5D-Y. No inconsistencies were observed. The minimum predicted score was 0.288 [33333], and the second-best score was 0.957 [12111]. Conclusion A value set for EQ-5D-Y was successfully constructed. This is the first survey of an EQ-5D-Y value set. Interpreting the differences between EQ-5D-Y and EQ-5D-5L value sets is a future task with implications for health care policy.

Keywords: composite TTO; discrete choice experiment; EQ-5D-Y; preference-based measure; QALY (search for similar items in EconPapers)
Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:41:y:2021:i:5:p:597-606

DOI: 10.1177/0272989X211001859

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