Choice of Intensive Lifestyle Change and/or Metformin after Shared Decision Making for Diabetes Prevention: Results from the Prediabetes Informed Decisions and Education (PRIDE) Study

Tannaz Moin, Jacqueline M. Martin, Carol M. Mangione, Jonathan Grotts, Norman Turk, Keith C. Norris, Chi-Hong Tseng, Kia Skrine Jeffers, Yelba Castellon-Lopez, Dominick L. Frosch and O. Kenrik Duru
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Tannaz Moin: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Jacqueline M. Martin: Johns Hopkins University, Baltimore, MD, USA
Carol M. Mangione: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Jonathan Grotts: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Norman Turk: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Keith C. Norris: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Chi-Hong Tseng: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Kia Skrine Jeffers: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Yelba Castellon-Lopez: David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Dominick L. Frosch: Palo Alto Medical Foundation for Health Care, Research and Education, Palo Alto, CA, USA
O. Kenrik Duru: David Geffen School of Medicine, University of California, Los Angeles, CA, USA

Medical Decision Making, 2021, vol. 41, issue 5, 607-613

Abstract: Introduction While the Diabetes Prevention Program Study demonstrated that intensive lifestyle change and metformin both reduce type 2 diabetes incidence, there are little data on patient preferences in real-world, clinical settings. Methods The Prediabetes Informed Decisions and Education (PRIDE) study was a cluster-randomized trial of shared decision making (SDM) for diabetes prevention. In PRIDE, pharmacists engaged patients with prediabetes in SDM using a decision aid with information about both evidence-based options. We recorded which diabetes prevention option(s) participants chose after the SDM visit. We also evaluated logistic regression models examining predictors of choosing intensive lifestyle change ± metformin, compared to metformin or usual care, and predictors of choosing metformin ± intensive lifestyle change, compared to intensive lifestyle change or usual care. Results Among PRIDE participants ( n = 515), 55% chose intensive lifestyle change, 8.5% chose metformin, 15% chose both options, and 21.6% declined both options. Women (odds ratio [OR] = 1.60, P = 0.023) had higher odds than men of choosing intensive lifestyle change. Patients >60 years old (OR = 0.50, P = 0.028) had lower odds than patients

Keywords: diabetes prevention; prediabetes; shared decision making (search for similar items in EconPapers)
Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:41:y:2021:i:5:p:607-613

DOI: 10.1177/0272989X211001279

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