Patients’ Attitude toward Less Frequent Surveillance of Low-Risk Pancreatic Cysts: A Multicenter European Cohort Study

Marloes L. J. A. Sprij, Inge M. C. M. de Kok, Daan D. Nieboer, Gabriele Capurso, Jihane Meziani, Mattheus C. B. Wielenga, Mirjam C. M. van der Ende, Marianne E. Smits, Riccardo Casadei, Matthijs P. Schwartz, Frederike G. I. van Vilsteren, Chantal Hoge, Rutger Quispel, Pieter Honkoop, Laurens A. van der Waaij, Gemma Rossi, Adriaan C. I. T. L. Tan, Marco J. Bruno and Djuna L. Cahen
Additional contact information
Marloes L. J. A. Sprij: Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands
Inge M. C. M. de Kok: Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
Daan D. Nieboer: Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
Gabriele Capurso: Department of Gastroenterology and Hepatology, Vita Salute San Raffaele University, Milan, Italy
Jihane Meziani: Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands
Mattheus C. B. Wielenga: Department of Gastroenterology & Hepatology, Amsterdam UMC, Amsterdam, The Netherlands
Mirjam C. M. van der Ende: Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, The Netherlands
Marianne E. Smits: Department of Gastroenterology & Hepatology, Tergooi, Hilversum, The Netherlands
Riccardo Casadei: Department of Surgery, Bologna University, Bologna, Italy
Matthijs P. Schwartz: Department of Gastroenterology & Hepatology, Meander Medical Center, Amersfoort, The Netherlands
Frederike G. I. van Vilsteren: Department of Gastroenterology & Hepatology, University Medical Center Groningen, Groningen, The Netherlands
Chantal Hoge: Department of Gastroenterology & Hepatology, Maastricht University Medical Center, Maastricht, The Netherlands
Rutger Quispel: Department of Gastroenterology & Hepatology, Reinier de Graaf hospital, Delft, The Netherlands
Pieter Honkoop: Department of Gastroenterology & Hepatology, Albert Schweitzer Hospital, Dordrecht, The Netherlands
Laurens A. van der Waaij: Department of Gastroenterology & Hepatology, Martini Hospital, Groningen, The Netherlands
Gemma Rossi: Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita Salute San Raffaele University, Milan, Italy
Adriaan C. I. T. L. Tan: Department of Gastroenterology & Hepatology, Canisius Wilhelmina hospital, Nijmegen, The Netherlands
Marco J. Bruno: Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands
Djuna L. Cahen: Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands

Medical Decision Making, 2025, vol. 45, issue 7, 904-912

Abstract: Background Recent studies show that low-risk pancreatic cysts may require less frequent monitoring. Future guidelines will likely adapt their recommendations accordingly. Our goal was to explore the willingness of individuals with a low-risk pancreatic cyst to undergo less frequent surveillance and to identify associated characteristics with such willingness. Methods This is a side study of the international PACYFIC study, which prospectively collects data on cyst surveillance, including questionnaires to assess participants’ attitude toward surveillance. Individuals with low-risk cysts at baseline, without given standardized information by the study protocol, were enrolled. Their responses to the baseline question, “Would you prefer less frequent surveillance? Yes/No,†were correlated with baseline characteristics using multivariable logistic regression, namely, age, country of residence, symptoms, medical and family history, time since first cyst detection, and Hospital Anxiety Depression Scale score. Results Of the 215 participants included from the Netherlands ( n = 185) and Italy ( n = 30), only 47 (22%) were willing to undergo less surveillance. Characteristics positively associated with this willingness were older age (odds ratio [OR] 1.87 per 10 y, 95% confidence interval [CI]: 1.15–3.04) and Italian residency (OR 16.35, 95% CI: 5.65–47.31). A medical history of cancer was negatively associated (OR 0.28, 95% CI: 0.09–0.90). No other associations were observed. Conclusion Most participants appear unwilling to undergo less frequent cyst surveillance. Older age and residing in Italy were associated with a greater willingness toward less rigorous surveillance, while a history of cancer did the opposite. Identifying which individuals are hesitant to undergo less frequent surveillance may help clinicians tailor their counseling and can support implementation of future guideline with fewer surveillance recommendations. Highlights Most low-risk individuals were reluctant toward less frequent pancreatic cyst surveillance. Older age and residency in Italy were associated with a higher willingness. A medical history of cancer was associated with an unwillingness. Standardized patient information may increase the willingness, but such information has yet to be developed.

Keywords: Pancreatic cyst surveillance; low-risk pancreatic cysts; patient atttitudes; surveillance frequency (search for similar items in EconPapers)
Date: 2025
References: Add references at CitEc
Citations:

Downloads: (external link)
https://journals.sagepub.com/doi/10.1177/0272989X251352750 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:45:y:2025:i:7:p:904-912

DOI: 10.1177/0272989X251352750

Access Statistics for this article

More articles in Medical Decision Making
Bibliographic data for series maintained by SAGE Publications ().