Objective Criteria for In-vitro Responses in Human Tumor Colony-forming Assays

James A. Koziol, A. John Petkau and Raymond Taetle

Medical Decision Making, 1988, vol. 8, issue 4, 304-309

Abstract: The application of rigorous statistical criteria to the design and analysis of in-vitro assay techniques can lead to more reliable assessments of their utility. The authors demonstrate that an objective criterion for in-vitro drug sensitivity would yield less pronounced false- negative error rates than a fixed-cutoff rule, and would therefore be more suitable for screen ing of putative chemotherapeutic agents. Key words: drug sensitivity testing; objective criteria. (Med Decis Making 8:304-309, 1988)

Date: 1988
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Persistent link: https://EconPapers.repec.org/RePEc:sae:medema:v:8:y:1988:i:4:p:304-309

DOI: 10.1177/0272989X8800800411

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