Applied Health Economics and Health Policy

2008 - 2026

Current editor(s): Timothy Wrightson

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Volume 24, issue 4, 2026

Indirect Effects in Health Economic Models of Vaccines: Should We Include Them, and How Do We Model Them? pp. 637-646

Rachel J. Oidtman, Min Huang, Walter A. Orenstein, Matthew S. Kelly, Zinan Yi, Elamin Elbasha and Michael Drummond

Integrating Equity in Topic Selection for Orphan Medicinal Products: Policy Implications for Health Technology Assessment in Rare Diseases pp. 647-654

Fatemeh Hosseini, Mohammadreza Mobinizadeh and William V. Padula

The Economic Value of Non-pharmaceutical Interventions for Influenza and COVID-19: A Systematic Review pp. 655-670

Hui Yee Yeo, Trinh Manh Hung, Nhung Nghiem, Steffen Albrecht, Nikki Turner and Peter McIntyre

Health Economic Evaluations of Breast Cancer Screening Strategies: A Systematic Review Focusing on Methodology and Quality Assessment pp. 671-689

Thi Hao Pham, Susan de Braak, Sjoukje van der Werf, Sudewi Mukaromah Khoirunnisa, Xuanqi Pan, Andre Pfob, Abrham Wondimu, Jurjen van der Schans, Maarten J. Postma, Antoinette D. I. van Asselt and Lisa A. de Jong

Lost in Translation? A Scoping Review to Explore the Translation and Cultural Adaptation of Preference-Based Measures of Quality of Life pp. 691-706

Jenny Cleland, Kiri Lay, Julie Ratcliffe and Jyoti Khadka

Estimating System-Wide Healthcare Costs Using a Health System Model: Application to the Thanzi La Onse Model of Malawi pp. 707-725

Sakshi Mohan, Newton Chagoma, Simon Walker, Christian Abraham Arega, Martin Chalkley, Joseph Collins, Emilia Connolly, Tim Colbourn, Eva Janoušková, Tara D. Mangal, Gerald Manthalu, Joseph Mfutso-Bengo, Margherita Molaro, Dominic Nkhoma, Andrew Phillips, Lalit Sharma, Bingling She, Wiktoria Tafesse, Pakwanja Desiree Twea, Paul Revill and Timothy B. Hallett

Agreement in Qualitative and Quantitative Assessments of Disease Severity: Evidence from Pharmaceutical Reimbursement in Sweden pp. 727-737

Martin Henriksson, Lars Sandman and Jonathan Siverskog

Quality-Adjusted Life Expectancy and Cost-Effectiveness Thresholds in Three High-Income Regions in Asia pp. 739-750

Xinyu Zhao and Yawen Jiang

Costs and Budget Impact of a Health System Strengthening Intervention for Hypertension and Cardiovascular Disease Care in Ghana pp. 751-762

Kavita Singh, Eugene Kallson, Elom Hillary Otchi, Rupal Shah-Rohlfs, Juliette Selom Edzeame, Fionn Harnischfeger, Alfred Edwin Yawson and Manuela De Allegri

Structured Expert Elicitation of Long-Term Survival in Non-small Cell Lung Cancer: A Case Study Applying Guidance from NICE Technical Support Document 26 pp. 763-776

Jessica E. Forsyth, Monika Achra, Javier Baena Espinar, Maximilian Hochmair, Astra M. Liepa, Alan Lenox-Smith, Tarun Puri, Rahul Rajesh, Michael D. Sonksen, Yvonne Summers, Anthonie J. van der Wekken, Min-Hua Jen and Shijie Ren

Cost Effectiveness of Endovascular Thrombectomy for Large Ischemic Strokes: A US Healthcare Payer Markov Model Informed by Randomized Trials pp. 777-789

Rami Z. Morsi, Yuan Zhang, Elena Badillo Goicoechea, Harsh Desai, Sachin A. Kothari, Sonam Thind, Archit B. Baskaran, Ahmad Chahine, James E. Siegler, Elisheva R. Coleman, James R. Brorson, Ali Mansour, Shyam Prabhakaran and Tareq Kass-Hout

Towards Environmentally Extended Health Economic Analysis Plans: A Case Study for the MEL-SELF Trial pp. 791-796

Jake T. W. Williams, Katy J. L. Bell, Scott McAlister and Rachael L. Morton

Volume 24, issue 3, 2026

It’s Time to Rethink ‘Real-World Evidence’: A Call for Terminological Clarity in Health Technology Assessment pp. 437-441

Hesam Ghiasvand and Haipeng Liu

The Increasing Value of Environmental Sustainability Assessments in Healthcare Policy and Technology Evaluation pp. 443-447

Lindsay Nicholson, Nick Pooley, Gregor Skeldon, Sue Langham, Antony Wright and Nina Embleton

Insights from Financial Economics to Value Healthcare Investments that Reduce System-Level Risks: Example of Disease Elimination and Eradication pp. 449-458

Megha Rao, Mark Freeman, Jacco Thijssen, Simon Bland, Mark Sculpher, Karl Claxton and Paul Revill

A Systematic Review of Microsimulation Models in Cardiometabolic Disease: Model Calibration and Validation pp. 459-478

Danwei Yang, Zhixin Cao, Jayoung Byun, Jong-Wook Ban and David D. Kim

Towards a Multi-sectoral Approach to Population Health: A Scoping Review of Cross-sectoral Evaluations of Health Interventions pp. 479-497

Rositsa Koleva-Kolarova, Emily Hulse, Bertalan Németh, Maureen Rutten- van Mölken, Rhiannon Tudor Edwards, Balázs Babarczy, Balázs Nagy, Sarah Wordsworth and Apostolos Tsiachristas

Should the Spanish National Health System Invest in Psychotherapy for Depression? A Microsimulation Cost-Utility Study to Estimate the Economically Justifiable Price of Cognitive Behavioral Therapy Versus Anti-depressant Medication pp. 499-516

Alberto de la Cuadra-Grande, Mónica Oltra-Díaz, Mara Lerma de Antonio, Miguel Ángel Casado and Itziar Oyagüez

Preferences of Women for Maternal Health Services in Sidama Region, Ethiopia: Discrete Choice Experiment pp. 517-539

Daniel Gashaneh Belay, Gizachew A. Tessema, Jennifer Dunne, Melaku Birhanu Alemu and Richard Norman

The Italian Assessment System for Innovative Medicines: An 8-Year Retrospective Analysis of Outcomes, Criteria, Timelines and Funding Dynamics pp. 541-551

Lorenzo Martellone, Camilla Servidio, Marcello Vaccaro, Katiuscja Malandrini, Adriana Coluccia, Alessandra Oliva, Claudio Maria Mastroianni and Giacomo Polito

Economic Evaluation of Bruton’s Tyrosine Kinase Inhibitors for Chronic Lymphocytic Leukaemia in South Africa pp. 553-566

Rochelle Woudberg and Edina Sinanovic

Policy Levers for First-Contact Healthcare Provider Choice: A Discrete Choice Experiment in Shanghai’s Hierarchical Medical System pp. 567-582

Yi Gong

Partnerships in Public Health Economics: Reflective Lessons from UK Obesity Research pp. 583-596

Humera Sultan, Nafsika Afentou, Luiz F. Andrade, Lin Fu, Bassit Malik, Hamideh Mohtashami Borzadaran, Bisola Osifowora, Irina Pokhilenko, Hanna Wride and Emma Frew

Cost-Effectiveness and Public Health Impact of Newborn Screening for Spinal Muscular Atrophy in France pp. 597-611

Sebastien Eymere, Oyin Opeifa, Aurélie Meunier, Marine Sivignon, Fanny Cayre, Aymeric de Chasteigner, Guillaume Leiba, Clément François, Didier Lacombe, Isabelle Borget and Vincent Laugel

Estimation of ‘spectrum value’: A discrete choice experiment to investigate the willingness-to-pay for narrow-spectrum based on other antimicrobial characteristics pp. 613-625

Nadine T. Hillock, Gang Chen, Tracy L. Merlin, Jennie Louise, John Turnidge and Jonathan Karnon

Ensuring Epidemiological Consistency in Risk-Stratified Cancer Screening Models: A Novel Approach Based on Flemish Breast Cancer Screening pp. 627-635

Max Lelie, Bo VandenBulcke, Nick Verhaeghe, Lieven Annemans, Steven Simoens and Koen Putman

Volume 24, issue 2, 2026

Politicised Changes to the NICE Threshold Risk Making Cost-Effectiveness Analysis Performative, Not Informative pp. 243-246

Laura Vallejo-Torres, Laura C. Edney, Oscar Espinosa Acuña, Jonathan Karnon, Francesco Longo, Mike Paulden, Daniel Howdon and David J. Vanness

Improving Consumer Engagement in Health Technology Assessment and Decision Making: Lessons from ‘Values in Science’ pp. 247-260

Isabella Carnovale, Kevin Elliott, Ian Kerridge and Wendy Lipworth

Opportunities for CMS to Further Specify and Broaden Its Approach to Assessing Unmet Medical Need in the Context of the Medicare Drug Price Negotiation Program pp. 261-269

Michael J. DiStefano, R. Brett McQueen, Hanke Zheng, Harry Gyimah Gyamfi, David Ameyaw, Jonathan D. Campbell and Antal Zemplenyi

Data-Related and Methodological Challenges in Assessing the Cost-Effectiveness of Traditional and Genomic Newborn Screening Programs pp. 271-286

Ramesh Lamsal, Hadley Stevens Smith and Scott D. Grosse

The Role of Price Variation in Economic Analyses for Cancer Screenings: A Rapid Review pp. 287-292

Austin J. Triana and Mason N. Alford-Holloway

Funding Multi-indication Medicines: A Scoping Review of Health Technology Assessment and Reimbursement Frameworks pp. 293-307

Isaiah Luc, Mah Laka, Drew Carter and Tracy Merlin

Do the Poor Gain More? The Impact of Secondary-Care Expenditure on Health Inequality pp. 309-324

Misael Anaya-Montes, Katja Grašič, James Lomas, Laura Anselmi, Miqdad Asaria, Christodoulos Kypridemos, Benjamin Barr, Matthew Sutton, Chris Bentley and Richard Cookson

Preferences for Digital Mental Health Services in Urban China: A Discrete Choice Experiment pp. 325-341

Defang Xiang, Yuling Qian and Di Liang

Health Technology Assessment Guidelines and Recommendations Across European Union Countries and the United Kingdom in Rare Disease and Paediatric Populations pp. 343-364

Adéla Bártová, Jiří Samek, Vera Pinheiro, Barbora Říhová and João Vasco Santos

Cost-Utility Analysis of TAVI Versus Surgery in Low-Risk Patients with Severe Aortic Stenosis in the UK pp. 365-378

Nick Curzen, Pascal Candolfi, Philip MacCarthy, Clinton T. Lloyd, Muhammad Aetesam-Ur-Rahman, Tom Bromilow, Valentina Sellitto and Daniel J. Blackman

Which Factors are Holding up the Integration of the Environmental Impact of Health Technologies in Health Technology Assessment? Insights from a Multi-Stakeholder Interview Study pp. 379-391

Vittoria Ardito, Helen Banks and Rosanna Tarricone

Budget Impact Analysis of Implementing C-Reactive Protein Point-of-Care Testing to Aid Antibiotic Prescribing in Belgian Primary Care pp. 393-405

Salima Azahaf, Erinn D’hulster, Margo Van Genechten, Thaddee Ding, Tibo Wynant, Jeroen Luyten and Jan Y. Verbakel

EQ-5D-5L Values and Determinants for a Vietnamese Population pp. 407-419

Nguyen Thanh Nam, Ngo Thi Tam, Nguyen Thi Lan Huong, Nguyen Tat Cuong, Pham Van Dem and Nguyen Hoang Thanh

A Cost–Utility Analysis of Surgical Site Infection Prevention: Broadening the Scope pp. 421-435

Agi McFarland, Sarkis Manoukian, Helen Mason and Jacqui Reilly

Volume 24, issue 1, 2026

A Reconciled Method for Evaluating the Cost-Effectiveness of Implementation Programmes: Illustrated by Quality Improvement Programmes to Increase the Uptake of Magnesium Sulphate in Preterm Births pp. 5-14

Carlos Sillero-Rejon, William Hollingworth, Brent C. Opmeer, Karen Luyt and Hugh McLeod

The Economics of Antibiotic Resistance: A Systematic Review and Meta-analysis Based on Global Research pp. 15-46

Sabela Siaba, Bruno Casal and Iván López-Martínez

Willingness to Pay per QALY: A Systematic Review of Demand-Side Valuations with a Focus on Age and Disease Severity pp. 47-63

Marios Athanasios Loupas, Kostas Athanasakis and Dimitris Zavras

Deriving Health Utility Values Using Mapping Methods Among the Chinese Population: A Systematic Review pp. 65-85

Shitong Xie, Tianqi Hong, Jialu Geng, Chang Luo, Haoran Fang and Jing Wu

A Systematic Review of Economic Evaluations on Interventions Targeting Insomnia or Hypersomnia pp. 87-110

Phuong Hong Le, Long Khanh-Dao Le, Dai Quy Le, Shantha M. W. Rajaratnam and Cathrine Mihalopoulos

A Systematic Review of Modelling Approaches in Economic Evaluations of Treatments for Inherited Bleeding Disorders pp. 111-129

Diaz M. Prameyllawati, Hester F. Lingsma, Marjon H. Cnossen and Renske M. T. Ten Ham

Mechanisms Considering Public Investment in Pricing and Reimbursement Decisions of Medicines and Other Health Technologies: A Scoping Review pp. 131-146

Mario García-Díaz, Zuzana Špacírová, Leticia García-Mochón and Jaime Espín

Burden of Disease in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Scoping Review pp. 147-161

Patricia Vester, Stefanos Boudouroglou-Walter, Jonas Schreyögg, Chantal Wieting and Christine Blome

Aligning Indigenous and Western Concepts of Health Resource Decision Making in a Western Canadian First Nations Context pp. 163-179

Aidan Neill, Stephanie Montesanti, Lea Bill, Barbara S. E. Verstraeten, Rhonda C. Bell, Richard T. Oster, Arto Ohinmaa and Mike Paulden

A Mixed-Methods Assessment of India’s Health Technology Assessment Ecosystem pp. 181-193

Yashika Chugh, Josyula K. Lakshmi, Pankaj Bahuguna, Navneet Kaur, Stephen Jan and Shankar Prinja

The Economic Cost of Obesity: A Cost-of-Illness Study in Greece pp. 195-215

Panagiotis Papantoniou and Nikolaos Maniadakis

Cost-Effectiveness of Deep Brain Stimulation for Advanced Parkinson’s Disease in Egypt pp. 217-230

Hesham Radwan, Zeiad Yousry Fayed, Tarek Elserry, Mazen T. Alkarras, Ali Shalash, Zahraa Hassan Shehata, Nour Walid Noureldin, Andrew Metry and Ahmed Kamel Basha

Healthcare Costs and Carbon Emissions of Stage III Melanoma Surveillance Imaging pp. 231-241

Jake T. W. Williams, Mbathio Dieng, Katy Bell, Scott McAlister and Rachael L. Morton