A Head-to-Head Comparison of UK SF-6D and Thai and UK EQ-5D-5L Value Sets in Thai Patients with Chronic Diseases

Phantipa Sakthong () and Wipaporn Munpan
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Phantipa Sakthong: Chulalongkorn University
Wipaporn Munpan: Phramongkutklao Hospital

Applied Health Economics and Health Policy, 2017, vol. 15, issue 5, No 12, 669-679

Abstract: Abstract Purpose Little was known about the head-to-head comparison of psychometric properties between SF-6D and EQ-5D-5L or the different value sets of EQ-5D-5L. Therefore, this study set out to compare the psychometric properties including agreement, convergent, and known-group validity between the SF-6D and the EQ-5D-5L using the real value sets from Thailand and the UK in patients with chronic diseases. Methods 356 adults taking a medication for at least 3 months were identified from a university hospital in Bangkok, Thailand, between July 2014 and March 2015. Agreement was assessed by intraclass correlation coefficients (ICCs) and Bland–Altman plots. Convergent validity was evaluated using Spearman’s rank correlation coefficients between SF-6D and EQ-5D-5L and EQ-VAS and SF-12v2. For known-groups validity, the Mann–Whitney U test and Kruskal–Wallis test were used to examine the associations between SF-6D and EQ-5D-5L and patient characteristics. Results Agreements between the SF-6D and the EQ-5D-5L using Thai and UK value sets were fair, with ICCs of 0.45 and 0.49, respectively. Bland-Altman plots showed that the majority of the SF-6D index scores were lower than the EQ-5D-5L index scores. Both the EQ-5D-5L value sets were more related to the EQ-VAS and physical health, while the SF-6D was more associated with mental health. Both EQ-5D-5L value sets were more sensitive than the SF-6D in discriminating patients with different levels of more known groups except for adverse drug reactions. Conclusions The SF-6D and both EQ-5D-5L value sets appeared to be valid but sensitive to different outcomes in Thai patients with chronic diseases.

Keywords: Index Score; Physical Component Summary; Mental Component Summary; Health Utility; Discrete Choice Experiment (search for similar items in EconPapers)
Date: 2017
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DOI: 10.1007/s40258-017-0320-3

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