Budget Impact Analysis of the Introduction of Subcutaneous Infliximab (CT-P13 SC) for the Treatment of Rheumatoid Arthritis in the United Kingdom

Han Geul Byun (), Minyoung Jang, Hyun Kyeong Yoo, James Potter and Taek Sang Kwon ()
Additional contact information
Han Geul Byun: Celltrion Healthcare
Minyoung Jang: Celltrion Healthcare
Hyun Kyeong Yoo: Celltrion Healthcare
James Potter: Celltrion Healthcare United Kingdom Limited
Taek Sang Kwon: Celltrion Healthcare

Applied Health Economics and Health Policy, 2021, vol. 19, issue 5, No 10, 735-745

Abstract: Abstract Background CT-P13 subcutaneous (SC)—the first and only SC version of infliximab—is approved by the European Medicines Agency for the treatment of rheumatoid arthritis (RA). This new mode of infliximab administration will allow patients to self-inject at home, significantly reducing the number of outpatient visits and costs of intravenous (IV) administration. This paper describes the economic impact of introducing CT-P13 SC to the market from the UK societal perspective. Objective The budget impact analysis was conducted to assess the financial impact of the adoption of CT-P13 SC over a 5-year period. Methods A prevalence-based budget impact model was developed incorporating epidemiological data, administration cost data, and market share data. The analysis compared a “world with” CT-P13 SC scenario to a “world without” CT-P13 SC. A sensitivity analysis included dose escalation up to 4.1 mg/kg to reflect the real-world care delivery setting. Results Compared to the “world without” scenario, the introduction of CT-P13 SC resulted in cost savings of ₤69.3 million in the UK over a 5-year period. In the scenario analysis, the saving increased to ₤173.5 million over 5 years. Conclusion Use of CT-P13 SC may lead to substantial cost savings for the UK society.

Date: 2021
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
http://link.springer.com/10.1007/s40258-021-00673-1 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:spr:aphecp:v:19:y:2021:i:5:d:10.1007_s40258-021-00673-1

Ordering information: This journal article can be ordered from
http://www.springer.com/economics/journal/40258

DOI: 10.1007/s40258-021-00673-1

Access Statistics for this article

Applied Health Economics and Health Policy is currently edited by Timothy Wrightson

More articles in Applied Health Economics and Health Policy from Springer
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().