Economic Effects of Fixed-Dose Versus Loose-Dose Combination Therapy for Type 2 Diabetes Patients

Anna-Katharina Böhm (), Udo Schneider and Tom Stargardt
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Anna-Katharina Böhm: University of Hamburg
Udo Schneider: Techniker Krankenkasse
Tom Stargardt: University of Hamburg

Applied Health Economics and Health Policy, 2023, vol. 21, issue 1, No 10, 109-118

Abstract: Abstract Objective We examined the effects of fixe-dose combinations (FDCs) versus loose-dose combinations (LDCs) on costs from the payer and patient perspective and investigated potential channels contributing to differences in costs between the two modes of treatment. Methods We investigated administrative data from 2017 to 2020 on diabetes patients in Germany. After using prospensity-score matching to remove dissimilarities between FDC and LDC patients, we compared changes in costs with a difference-in-differences approach. We analyzed pharmaceutical costs, inpatient and outpatient costs, other costs and total healthcare costs from the payer perspective, and co-payments from the patient perspective. Results The sample comprised 1117 FDC and 1272 LDC patients. Regression analysis revealed that FDC therapy significantly increased antidiabetic pharmaceutical spending in the first year by 5.5% (p

Date: 2023
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DOI: 10.1007/s40258-022-00760-x

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