Development of an Instrument for the Assessment of Health-Related Multi-sectoral Resource Use in Europe: The PECUNIA RUM

Irina Pokhilenko (), Luca M. M. Janssen, Aggie T. G. Paulus, Ruben M. W. A. Drost, William Hollingworth, Joanna C. Thorn, Sian Noble, Judit Simon, Claudia Fischer, Susanne Mayer, Luis Salvador-Carulla, Alexander Konnopka, Leona Hakkaart van Roijen, Valentin Brodszky, A-La Park and Silvia M. A. A. Evers
Additional contact information
Irina Pokhilenko: Maastricht University
Luca M. M. Janssen: Maastricht University
Aggie T. G. Paulus: Maastricht University
Ruben M. W. A. Drost: Maastricht University
William Hollingworth: University of Bristol
Joanna C. Thorn: University of Bristol
Sian Noble: University of Bristol
Judit Simon: Medical University of Vienna
Claudia Fischer: Medical University of Vienna
Susanne Mayer: Medical University of Vienna
Luis Salvador-Carulla: University of Canberra
Alexander Konnopka: University Medical Center Hamburg
Leona Hakkaart van Roijen: Erasmus University of Rotterdam
A-La Park: London School of Economics and Political Science
Silvia M. A. A. Evers: Maastricht University

Applied Health Economics and Health Policy, 2023, vol. 21, issue 2, No 1, 155-166

Abstract: Abstract Background Measuring objective resource-use quantities is important for generating valid cost estimates in economic evaluations. In the absence of acknowledged guidelines, measurement methods are often chosen based on practicality rather than methodological evidence. Furthermore, few resource-use measurement (RUM) instruments focus on the measurement of resource use in multiple societal sectors and their development process is rarely described. Thorn and colleagues proposed a stepwise approach to the development of RUM instruments, which has been used for developing cost questionnaires for specific trials. However, it remains unclear how this approach can be translated into practice and whether it is applicable to the development of generic self-reported RUM instruments and instruments measuring resource use in multiple sectors. This study provides a detailed description of the practical application of this stepwise approach to the development of a multi-sectoral RUM instrument developed within the ProgrammE in Costing, resource use measurement and outcome valuation for Use in multi-sectoral National and International health economic evaluAtions (PECUNIA) project. Methods For the development of the PECUNIA RUM, the methodological approach was based on best practice guidelines. The process included six steps, including the definition of the instrument attributes, identification of cost-driving elements in each sector, review of methodological literature and development of a harmonized cross-sectorial approach, development of questionnaire modules and their subsequent harmonization. Results The selected development approach was, overall, applicable to the development of the PECUNIA RUM. However, due to the complexity of the development of a multi-sectoral RUM instrument, additional steps such as establishing a uniform methodological basis, harmonization of questionnaire modules and involvement of a broader range of stakeholders (healthcare professionals, sector-specific experts, health economists) were needed. Conclusion This is the first study that transparently describes the development process of a generic multi-sectoral RUM instrument in health economics and provides insights into the methodological aspects and overall validity of its development process.

Date: 2023
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DOI: 10.1007/s40258-022-00780-7

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