Measuring the Burden of Schizophrenia Using Clinician and Patient-Reported Measures: An Exploratory Analysis of Construct Validity

Matthew Franklin (), Clara Mukuria, Brendan Mulhern, Irwin Tran, John Brazier and Stuart Watson
Additional contact information
Matthew Franklin: Health Economics and Decision Science (HEDS), School of Health and Related Research (ScHARR), University of Sheffield
Clara Mukuria: Health Economics and Decision Science (HEDS), School of Health and Related Research (ScHARR), University of Sheffield
Brendan Mulhern: Health Economics and Decision Science (HEDS), School of Health and Related Research (ScHARR), University of Sheffield
Irwin Tran: Health Economics and Strategic Pricing, Roche Products Limited
John Brazier: Health Economics and Decision Science (HEDS), School of Health and Related Research (ScHARR), University of Sheffield
Stuart Watson: Newcastle University

The Patient: Patient-Centered Outcomes Research, 2019, vol. 12, issue 4, No 6, 405-417

Abstract: Abstract Background Various self-reported or clinician-reported (as a proxy) measures exist to quantify the burden of schizophrenia on patients. Evidence of the psychometric relationship between these measures to inform their practical use is limited. Objectives Our objective was to conduct an exploratory analysis of the construct validity of patient-reported (EQ-5D, SF-6D, WEMWBS, SQLS subscales of Psychosocial, Motivation, Symptoms) versus clinician-reported measures (PANSS, CGI-SCH, NSA-4, HoNOS-PbR) to inform future use of patient-reported measures for burden-of-illness assessment and/or economic evaluation. Methods In an adult patient population with schizophrenia, construct validity was assessed in relation to convergent and known-group validity. Convergent validity was assessed using Spearman’s rank absolute correlation strength (ACS: weak ≤ 0.3, moderate = 0.3

Date: 2019
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
http://link.springer.com/10.1007/s40271-019-00358-x Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:spr:patien:v:12:y:2019:i:4:d:10.1007_s40271-019-00358-x

Ordering information: This journal article can be ordered from
http://www.springer.com/economics/journal/40271

DOI: 10.1007/s40271-019-00358-x

Access Statistics for this article

The Patient: Patient-Centered Outcomes Research is currently edited by Christopher I. Carswell

More articles in The Patient: Patient-Centered Outcomes Research from Springer, International Academy of Health Preference Research
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().