The Cost Effectiveness of Newer Epilepsy Treatments

Kristian Bolin and Lars Forsgren

PharmacoEconomics, 2012, vol. 30, issue 10, 903-923

Abstract: Although failure to meet good practice guidelines influences the reliability of the presented evidence adversely, a sufficient number of the included studies were found to comply enough with the guidelines in order for the qualitative content of the cost-effectiveness results — that some of the newer AEDs are cost effective — to be reliable. In fact, this conclusion is likely to be relatively robust, since the effect of improved seizure control on labour market performance was not included in the base-case results in any of the included studies and improved seizure control need only to have a moderate effect on sickness absenteeism in order for the corresponding treatment to be cost effective even when willingness to pay for an additional QALY is low. However, the cost effectiveness of newer AEDs has only been studied for a small number of settings, and hence future studies incorporating additional settings are needed. Copyright Springer International Publishing Switzerland 2012

Date: 2012
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DOI: 10.2165/11597110-000000000-00000

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