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Mapping Between the Sydney Asthma Quality of Life Questionnaire (AQLQ-S) and Five Multi-Attribute Utility Instruments (MAUIs)

Billingsley Kaambwa (), Gang Chen (), Julie Ratcliffe, Angelo Iezzi, Aimee Maxwell and Jeff Richardson
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Billingsley Kaambwa: Flinders University, A Block, Repatriation General Hospital
Julie Ratcliffe: Flinders University, A Block, Repatriation General Hospital
Angelo Iezzi: Monash University
Aimee Maxwell: Monash University
Jeff Richardson: Monash University

PharmacoEconomics, 2017, vol. 35, issue 1, 111-124

Abstract: Abstract Purpose Economic evaluation of health services commonly requires information regarding health-state utilities. Sometimes this information is not available but non-utility measures of quality of life may have been collected from which the required utilities can be estimated. This paper examines the possibility of mapping a non-utility-based outcome, the Sydney Asthma Quality of Life Questionnaire (AQLQ-S), onto five multi-attribute utility instruments: Assessment of Quality of Life 8 Dimensions (AQoL-8D), EuroQoL 5 Dimensions 5-Level (EQ-5D-5L), Health Utilities Index Mark 3 (HUI3), 15 Dimensions (15D), and the Short-Form 6 Dimensions (SF-6D). Methods Data for 856 individuals with asthma were obtained from a large Multi-Instrument Comparison (MIC) survey. Four statistical techniques were employed to estimate utilities from the AQLQ-S. The predictive accuracy of 180 regression models was assessed using six criteria: mean absolute error (MAE), root mean squared error (RMSE), correlation, distribution of predicted utilities, distribution of residuals, and proportion of predictions with absolute errors

Date: 2017
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DOI: 10.1007/s40273-016-0446-4

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