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Cryosurgery planning using bubble packing in 3D

Daigo Tanaka, Kenji Shimada, Michael R. Rossi and Yoed Rabin

Computer Methods in Biomechanics and Biomedical Engineering, 2008, vol. 11, issue 2, 113-121

Abstract: As part of an ongoing project to develop automated tools for cryosurgery planning, the current study focuses on the development of a 3D bubble packing method. A proof-of-concept for the new method is demonstrated on five prostate models, reconstructed from ultrasound images. The new method is a modification of an established method in 2D. Ellipsoidal bubbles are packed in the volume of the prostate in the current study; such bubbles can be viewed as a first-order approximation of a frozen region around a single cryoprobe. When all cryoprobes are inserted to the same depth, optimum planning was found to occur at about 60% of the length of the prostate (measured from its apex), which leads to cooling of approximately 75% of the prostate volume below a specific temperature threshold of − 22°C. Bubble packing has the potential to dramatically reduce the run time for automated planning.

Date: 2008
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DOI: 10.1080/10255840701336653

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Computer Methods in Biomechanics and Biomedical Engineering is currently edited by Director of Biomaterials John Middleton

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