Numerical simulation of the flow field and mass transport pattern within the coronary artery

Nenad Filipovic, Danko Milasinovic, Nikola Jagic, Vladimir Miloradovic, Holger Hetterich and Johannes Rieber

Computer Methods in Biomechanics and Biomedical Engineering, 2011, vol. 14, issue 04, 379-388

Abstract: In this study, the steady and pulsatile flow field with mass transport analysis in an anatomically correct model of coronary artery is simulated numerically using a specific patient data from a 64-multislice computed tomography scanner. It is assumed that the blood flow is laminar and that the Navier–Stokes equations of motion are applied. Downstream of the bifurcation, a strong skewing occurs towards the flow divider walls as a result of branching. For the low-density lipoprotein (LDL) transport analysis where a specific boundary condition at the arterial walls is applied, LDL is generally elevated at locations where shear stress distribution is low, but it does not co-locate at whole domain. This numerical simulation gives an insight, as well as detailed quantitative data, of haemodynamic conditions in the left coronary artery as well as mass transfer patterns for a specific patient.

Date: 2011
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DOI: 10.1080/10255842.2010.482526

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