A methodology for numerically analysing the hepatic artery haemodynamics during B-TACE: a proof of concept

Jorge Aramburu, Raúl Antón, Alejandro Rivas, Juan Carlos Ramos, Gorka S. Larraona, Bruno Sangro and José Ignacio Bilbao

Computer Methods in Biomechanics and Biomedical Engineering, 2019, vol. 22, issue 5, 518-532

Abstract: Balloon-occluded transarterial chemoembolisation (B-TACE) is an intraarterial transcatheter treatment for liver cancer. In B-TACE, an artery-occluding microballoon catheter occludes an artery and promotes collateral circulation for drug delivery to tumours. This paper presents a methodology for analysing the haemodynamics during B-TACE, by combining zero-dimensional and three-dimensional modelling tools. As a proof of concept, we apply the methodology to a patient-specific hepatic artery geometry and analyse two catheter locations. Results show that the blood flow redistribution can be predicted in this proof-of-concept study, suggesting that this approach could potentially be used to optimise catheter location.

Date: 2019
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DOI: 10.1080/10255842.2019.1567720

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