Bone fracture healing within a continuum bone remodelling framework

Ina Schmidt, Jacob Albert, Marina Ritthaler, Areti Papastavrou and Paul Steinmann

Computer Methods in Biomechanics and Biomedical Engineering, 2022, vol. 25, issue 9, 1040-1050

Abstract: Bone fracture healing is a complex process which is still under research. Computer-aided patient-specific prediction of bone development, fracture risk, prevention and treatment approaches promises a significant milestone in clinical practice. With this long-term goal in mind, a novel model is presented and examined in this work in the context of continuum bone remodelling. Therein, a clear distinction is made between external mechanical stimulation and the biological healing process of an injured bone tissue. The model is implemented within a finite element framework and investigated for the example of a fractured proximal femur head. The results show promising perspectives for further application. Besides, the model offers the possibility of easily integrating other factors like age-dependency and the availability of nutrition. For the future, further studies with large clinical datasets are essential for validation.

Date: 2022
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DOI: 10.1080/10255842.2021.1998465

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