Development of an additively-manufactured functionally-graded expandable implant via the application of the adaptive response surface method: feasibility study on intramedullary humerus nail

Aleš Hrouda, Petr Obruba, Lukas Capek, Jiri Safka, Veronika Truxova and Stefan Rammelt

Computer Methods in Biomechanics and Biomedical Engineering, 2023, vol. 26, issue 9, 999-1007

Abstract: The paper introduces the concept of the rational design of a deployable humeral intramedullary nail plug based on a honeycomb structure used for the surgical treatment of humeral shaft fractures. The concept serves for to restore the axial alignment of bone fragments and to maintain stability via bone-nail friction and locking screws. The design nail plug was gained by optimisation process the Latin Hypercube Sampling Design algorithm and Multi-Objective Genetic Algorithm. It was shown that we can use statistical shape function combined by 3 D printing for designing of a new rationally designed implants.

Date: 2023
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DOI: 10.1080/10255842.2022.2100988

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