Bayesian discrete latent spatial modeling of crack initiation in orthopaedic hip replacement bone cement

Elizabeth Heron and Cathal Walsh

Journal of Applied Statistics, 2010, vol. 37, issue 7, 1153-1171

Abstract: In this paper, we propose a spatial model for the initiation of cracks in the bone cement of hip replacement specimens. The failure of hip replacements can be attributed mainly to damage accumulation, consisting of crack initiation and growth, occurring in the cement mantle that interlocks the hip prosthesis and the femur bone. Since crack initiation is an important factor in determining the lifetime of a replacement, the understanding of the reasons for crack initiation is vital in attempting to prolong the life of the hip replacement. The data consist of crack location coordinates from five laboratory experimental models, together with stress measurements. It is known that stress plays a major role in the initiation of cracks, and it is also known that other unmeasurable factors such as air bubbles (pores) in the cement mantle are also influential. We propose an identity-link spatial Poisson regression model for the counts of cracks in discrete regions of the cement, incorporating both the measured (stress), and through a latent process, any unmeasured factors (possibly pores) that may be influential. All analysis is carried out in a Bayesian framework, allowing for the inclusion of prior information obtained from engineers, and parameter estimation for the model is done via Markov chain Monte Carlo techniques.

Keywords: orthopaedic hip replacement; crack initiation; identity-link Poisson regression; latent spatial process; Bayesian analysis; Markov chain Monte Carlo; zero-inflated Poisson (search for similar items in EconPapers)
Date: 2010
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DOI: 10.1080/02664760902939620

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