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Jingxiang Chen, Yufeng Liu, Donglin Zeng, Rui Song, Yingqi Zhao and Michael R. Kosorok

Journal of the American Statistical Association, 2016, vol. 111, issue 515, 942-947

Abstract: Xu, Müller, Wahed, and Thall proposed a Bayesian model to analyze an acute leukemia study involving multi-stage chemotherapy regimes. We discuss two alternative methods, Q-learning and O-learning, to solve the same problem from the machine learning point of view. The numerical studies show that these methods can be flexible and have advantages in some situations to handle treatment heterogeneity while being robust to model misspecification.

Date: 2016
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DOI: 10.1080/01621459.2016.1200914

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