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Brief mindfulness-oriented interventions (MOIs) to improve psychiatric symptoms in a psychiatric inpatient unit: a randomized controlled feasibility trial

Ghizlane Moussaoui, Christina Rigas, Sophia Escobar, S. Gabriela Torres-Platas, Saulo Castel, Michelle Yang, Joseph Inhaber, Julia Novielli, Juliana Van Amsterdam, Neeti Sasi, Angela Potes, Katerina Nikolitch, Romeo Penheiro, Karl Looper, Marilyn Segal, Dominique Elie, Alex Kiss, Steven Selchen, Nathan Hermann, Harmehr Sekhon and Soham Rej

Psychosis, 2022, vol. 14, issue 4, 368-377

Abstract: BackgroundMindfulness-based interventions are effective in treating numerous psychiatric symptoms, but data about brief mindfulness-oriented intervention (MOI) use with psychiatric inpatients are limited. We investigated whether a brief MOI was feasible and effective in reducing psychosis and other symptoms in a psychiatric inpatient unit.MethodsIn an assessor-blinded feasibility randomized-controlled trial, adult psychiatric inpatients were randomized to the intervention or control group. Feasibility outcomes included enrollment rate, retention rate and intervention-completion rate. The quantitative outcome was the impact on symptom reduction (mean and % difference in Brief Psychiatric Rating Scale (BPRS) between baseline and 7-day follow-up scores). Exploratory outcomes included improvement in quality of sleep, mindfulness and quality of life. Qualitative intervention feedback was obtained from therapists and participants.ResultsFeasibility outcomes were 39.2% participant enrollment, 85% study completion and 81.8% intervention completion. No symptom outcomes significantly differed. There were no significant differences in exploratory outcomes. Interventionists reported system-level barriers in treatment delivery; patients subjectively reported enjoying the intervention.DiscussionThe MOI is feasible in the inpatient psychiatric setting. There were no significant effects on psychiatric symptoms during the follow-up period, but no adverse effects were reported. Therapeutic effects could be further investigated in longer-term interventions and larger confirmatory RCTs.

Date: 2022
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DOI: 10.1080/17522439.2021.1978530

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