How Tautological Are Interspecies Correlations of Carcinogenic Potencies?

David A. Freedman, Lois Swirsky Gold and Thomas H. Slone

Risk Analysis, 1993, vol. 13, issue 3, 265-272

Abstract: Crouch and Wilson demonstrated a strong correlation between carcinogenic potencies in rats and mice, supporting the extrapolation from mouse to man. Bernstein et al., however, show that the observed correlation is mainly a statistical artifact of bioassay design. Crouch et al. have a comeback. This paper will review the arguments and present some new data. The correlation is largely (but not totally) tautological, confirming results in Bernstein et al.

Date: 1993
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https://doi.org/10.1111/j.1539-6924.1993.tb01078.x

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Persistent link: https://EconPapers.repec.org/RePEc:wly:riskan:v:13:y:1993:i:3:p:265-272

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