Some Properties of the Hazard Function of the Two‐Mutation Clonal Expansion Model

Wolfgang F. Heidenreich, E. Georg Luebeck and Suresh H. Moolgavkar

Risk Analysis, 1997, vol. 17, issue 3, 391-399

Abstract: We discuss the hazard function of the two‐mutation clonal expansion model with time‐dependent parameters, with particular emphasis on identifiability of the parameters. We explicitly construct identifiable parameter combinations, and illustrate the properties of the hazard function under perturbations of the underlying biological parameters.

Date: 1997
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Citations: View citations in EconPapers (6)

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https://doi.org/10.1111/j.1539-6924.1997.tb00878.x

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Persistent link: https://EconPapers.repec.org/RePEc:wly:riskan:v:17:y:1997:i:3:p:391-399

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