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Predictive Genetic Testing for Alzheimer's Disease: Impact upon Risk Perception

Theresa M. Marteau, Scott Roberts, Susan LaRusse and Robert C. Green

Risk Analysis, 2005, vol. 25, issue 2, 397-404

Abstract: The aim of this study was to determine the impact on risk perceptions of disclosing genetic test results used to estimate the risk of Alzheimer's disease (AD). Adult children (n= 149) of people with AD were randomized to one of two groups—Intervention group: lifetime risk estimates of AD based on age, gender, family history, and Apolipoprotein E (APOE) genotype; Control group: lifetime risk estimates of AD based on the same risk factors excluding APOE genotype. Perceptions of personal risk (PPR) for AD were assessed six weeks after risk assessments. PPR were correlated with actual lifetime risk estimates (r= 0.501; p

Date: 2005
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https://doi.org/10.1111/j.1539-6924.2005.00598.x

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Persistent link: https://EconPapers.repec.org/RePEc:wly:riskan:v:25:y:2005:i:2:p:397-404

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