Perspective: Determinants of the Severity of Poliovirus Outbreaks in the Post Eradication Era

P. E. M. Fine and S. Ritchie

Risk Analysis, 2006, vol. 26, issue 6, 1533-1540

Abstract: The potential consequences of the reintroduction of poliovirus in the post‐eradication era range from trivial (no or self‐limited transmission and no clinical cases) to very serious (return of continued transmission of polioviruses and abandonment of the poliomyelitis eradication goal). This paper summarises the key determinants of such outcomes and identifies factors relating to infection surveillance, to vaccination policies at the time of OPV cessation and beyond, and to the still‐unknown implications of these policies for infection transmission in environments with poor sanitation, as particularly important. Explicit consideration of these issues should encourage studies on the effectiveness of IPV vaccines in reducing poliovirus transmission in tropical environments, and should influence the location and containment requirements of facilities for vaccine production and storage, and for poliovirus‐related research, in the era after cessation of OPV.

Date: 2006
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://doi.org/10.1111/j.1539-6924.2006.00855.x

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:wly:riskan:v:26:y:2006:i:6:p:1533-1540

Access Statistics for this article

More articles in Risk Analysis from John Wiley & Sons
Bibliographic data for series maintained by Wiley Content Delivery ().