Benzene Risk Estimation Using Radiation Equivalent Coefficients

Aki Nakayama, Tomomi Isono, Takuro Kikuchi, Iichiro Ohnishi, Junichiro Igarashi, Minoru Yoneda and Shinsuke Morisawa

Risk Analysis, 2009, vol. 29, issue 3, 380-392

Abstract: We estimated benzene risk using a novel framework of risk assessment that employed the measurement of radiation dose equivalents to benzene metabolites and a PBPK model. The highest risks for 1 μg/m3 and 3.2 mg/m3 life time exposure of benzene estimated with a linear regression were 5.4 × 10−7 and 1.3 × 10−3, respectively. Even though these estimates were based on in vitro chromosome aberration test data, they were about one‐sixth to one‐fourteenth that from other studies and represent a fairly good estimate by using radiation equivalent coefficient as an “internal standard.”

Date: 2009
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://doi.org/10.1111/j.1539-6924.2008.01174.x

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:wly:riskan:v:29:y:2009:i:3:p:380-392

Access Statistics for this article

More articles in Risk Analysis from John Wiley & Sons
Bibliographic data for series maintained by Wiley Content Delivery ().