Validation of an efficient two-dimensional model for dense suspensions of red blood cells

Lampros Mountrakis (), Eric Lorenz () and Alfons G. Hoekstra ()
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Lampros Mountrakis: Computational Science Research Group, Faculty of Science, University of Amsterdam, The Netherlands
Eric Lorenz: Computational Science Research Group, Faculty of Science, University of Amsterdam, The Netherlands
Alfons G. Hoekstra: Computational Science Research Group, Faculty of Science, University of Amsterdam, The Netherlands

International Journal of Modern Physics C (IJMPC), 2014, vol. 25, issue 12, 1-9

Abstract: Many rheological properties of blood, along with transport properties of blood cells can be captured by means of modeling blood through its main constituents, red blood cells (RBCs) and plasma. In the current work, we present a fully resolved two-dimensional model for blood suspension flow, employing a discrete element model (DEM) for RBCs and coupling it to a lattice Boltzmann method (LBM) fluid solver using the immersed boundary method (IBM). We identify an efficient computationally reduced mesoscopic representation of cells and flow, still able to recover essential physics and physiological phenomena. Our model is found to agree quantitatively with experimental findings. The Fåhræus–Lindqvist effect and shear thinning is recovered, while the thickness of the cell-free layer (CFL) matches the observations. In addition, we investigate the tank-treading frequency of a single RBC in shear flow along with the transition from tumbling to tank-treading, also matching experimental data.

Keywords: Blood; red blood cells; suspension; IBM; LBM; 47.63.- b; 47.61.Jd (search for similar items in EconPapers)
Date: 2014
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DOI: 10.1142/S0129183114410058

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