Three-band decomposition analysis in multiscale FSI models of abdominal aortic aneurysms

Maria G. C. Nestola (), Alessio Gizzi, Christian Cherubini and Simonetta Filippi
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Maria G. C. Nestola: Nonlinear Physics and Mathematical Modeling LaboratoryUniversity Campus Bio-Medico of Rome Via Alvaro del Portillo 21, 00128 Rome, Italy
Alessio Gizzi: Nonlinear Physics and Mathematical Modeling LaboratoryUniversity Campus Bio-Medico of Rome Via Alvaro del Portillo 21, 00128 Rome, Italy
Christian Cherubini: Nonlinear Physics and Mathematical Modeling LaboratoryUniversity Campus Bio-Medico of Rome Via Alvaro del Portillo 21, 00128 Rome, Italy2International Center for Relativistic Astrophysics Network, I.C.R.A.Net
Simonetta Filippi: Nonlinear Physics and Mathematical Modeling LaboratoryUniversity Campus Bio-Medico of Rome Via Alvaro del Portillo 21, 00128 Rome, Italy2International Center for Relativistic Astrophysics Network, I.C.R.A.Net

International Journal of Modern Physics C (IJMPC), 2016, vol. 27, issue 02, 1-19

Abstract: Computational modeling plays an important role in biology and medicine to assess the effects of hemodynamic alterations in the onset and development of vascular pathologies. Synthetic analytic indices are of primary importance for a reliable and effective a priori identification of the risk. In this scenario, we propose a multiscale fluid-structure interaction (FSI) modeling approach of hemodynamic flows, extending the recently introduced three-band decomposition (TBD) analysis for moving domains. A quantitative comparison is performed with respect to the most common hemodynamic risk indicators in a systematic manner. We demonstrate the reliability of the TBD methodology also for deformable domains by assuming a hyperelastic formulation of the arterial wall and a Newtonian approximation of the blood flow. Numerical simulations are performed for physiologic and pathologic axially symmetric geometry models with particular attention to abdominal aortic aneurysms (AAAs). Risk assessment, limitations and perspectives are finally discussed.

Keywords: Fluid-structure interaction; multiscale modeling; wall shear stress; hemodynamics (search for similar items in EconPapers)
Date: 2016
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DOI: 10.1142/S0129183116500170

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