Introducing Complexity in the Equation: How Pfizer Made Complexity on a Plant Level Transparent

Colin Seller (), Richard Davis (), Matthias Götzfried () and Thomas Friedli ()
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Colin Seller: Pfizer
Richard Davis: Pfizer
Matthias Götzfried: Freudenberg Sealing Technologies
Thomas Friedli: University of St.Gallen

Chapter Chapter 19 in Leading Pharmaceutical Operational Excellence, 2013, pp 323-335 from Springer

Abstract: Abstract Managing complexity induced by product variety represents a major challenge for every industrial company in this world. In the Pharmaceutical Industry the regulatory requirements make the situation even more challenging. Companies are especially concerned with the assessment of variety-induced complexity at production plants and its impact on operational performance. This chapter describes how Pfizer examined the connection between Complexity and Operational Excellence on the plant level and the potential for using the model for identification of operational improvements on the plant, as well as the broader manufacturing network level. The chapter follows a methodical combination of qualitative and quantitative approaches and presents a complexity index consisting of 20 indicators. Taking the index as a basis, the relationship between complexity and operational plant performance is investigated. Finally, two clusters, built on plant performance level and ability to transfer high external complexity into low internal complexity, are compared in detail. In the concluding part, the benefit for Pfizer from taking this perspective and approach on plant performance and on OPEX is described.

Keywords: Production Plant; Operational Performance; Mass Customization; Complexity Index; Product Portfolio (search for similar items in EconPapers)
Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:spr:sprchp:978-3-642-35161-7_19

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DOI: 10.1007/978-3-642-35161-7_19

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