The role of the geometric mean in case-control studies

Amanda Coston and Edward H. Kennedy

Papers from arXiv.org

Abstract: Historically used in settings where the outcome is rare or data collection is expensive, outcome-dependent sampling is relevant to many modern settings where data is readily available for a biased sample of the target population, such as public administrative data. Under outcome-dependent sampling, common effect measures such as the average risk difference and the average risk ratio are not identified, but the conditional odds ratio is. Aggregation of the conditional odds ratio is challenging since summary measures are generally not identified. Furthermore, the marginal odds ratio can be larger (or smaller) than all conditional odds ratios. This so-called non-collapsibility of the odds ratio is avoidable if we use an alternative aggregation to the standard arithmetic mean. We provide a new definition of collapsibility that makes this choice of aggregation method explicit, and we demonstrate that the odds ratio is collapsible under geometric aggregation. We describe how to partially identify, estimate, and do inference on the geometric odds ratio under outcome-dependent sampling. Our proposed estimator is based on the efficient influence function and therefore has doubly robust-style properties.

Date: 2022-07
New Economics Papers: this item is included in nep-ecm
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
http://arxiv.org/pdf/2207.09016 Latest version (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:arx:papers:2207.09016

Access Statistics for this paper

More papers in Papers from arXiv.org
Bibliographic data for series maintained by arXiv administrators ().