Valuing Pharmaceutical Drug Innovations
Federico Ciliberto,
Leland Farmer,
Ekaterina Khmelnitskaya and
Gaurab Aryal
No 20302, CEPR Discussion Papers from Centre for Economic Policy Research
Abstract:
We propose a methodology to estimate the market value of pharmaceutical drugs. Our approach combines the event study method with a discounted cash flow model that infers drug values from stock market responses to drug development announcements. We estimate the average value of a drug developed by small firms (those below the 95th percentile of market capitalization) to be $2.16 billion. At the preclinical stage, the risk-adjusted and present discounted average net value of drugs is $50 million. Leveraging these estimates, we also determine the expected drug development cost at the start of the discovery stage to be $38 million. We estimate values and costs for several therapeutic areas (e.g., neoplasm, infections) and explore applying these estimates to design policies that support drug development through drug buyouts and targeted preclinical interventions.
JEL-codes: G14 L65 O31 (search for similar items in EconPapers)
Date: 2025-05
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