Impacts of Patent Expiry and Regulatory Policies on Daily Cost of Pharmaceutical Treatments: OECD Countries, 2004-2010

Ernst R Berndt and Pierre Dubois

No 9140, CEPR Discussion Papers from C.E.P.R. Discussion Papers

Abstract: Cross-country variability in regulatory frameworks, industrial policy, physician/pharmacy autonomy, brand/generic distinctions, and in the practice of medicine contributes to ambiguous interpretations of pharmaceutical cost comparisons. Here we report cross-country comparisons that: (i) focus on 11 therapeutic classes experiencing patent expiration and loss of exclusivity 2004-2010 in eight industrialized countries; (ii) convert revenues and unit sales to cost per day of treatment and number patient days treated using the World Health Organizations? Defined Daily Dosage metrics; (iii) compare patterns in costs per day of treatment with price index measures based on average price per day of treatment for each molecule computed over all molecule versions; (iv) utilizing econometric methods, model and quantify various factors affecting variations in daily treatment price indexes such as national regulatory and reimbursement policy changes, physician/pharmacy autonomy, and other factors; and (v) simulate changes in expenditures by country and therapeutic class had counterfactual policies been implemented.

Keywords: Cross-country comparisons; Generic drugs; Pharmaceutical costs (search for similar items in EconPapers)
JEL-codes: D4 I11 I18 L11 L65 O34 (search for similar items in EconPapers)
Date: 2012-09
New Economics Papers: this item is included in nep-com, nep-hea, nep-ipr and nep-pr~
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Citations: View citations in EconPapers (9)

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Related works:
Working Paper: Impacts of Patent Expiry and Regulatory Policies on Daily Cost of Pharmaceutical Treatments: OECD Countries, 2004-2010 (2012)
Working Paper: Impacts of Patent Expiry and Regulatory Policies on Daily Cost of Pharmaceutical Treatments: OECD Countries, 2004-2010 (2012)
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