A cost effectiveness analysis of maintenance cognitive stimulation therapy (MCST) for people with dementia: examining the influence of cognitive ability and living arrangements

Heather Brown, Francesco D'Amico, Martin Knapp, Martin Orrell, Amritpal Rehill, Luke Vale and Louise Robinson

LSE Research Online Documents on Economics from London School of Economics and Political Science, LSE Library

Abstract: Objectives: Identify if cost-effectiveness of Maintenance Cognitive Simulation Therapy (MCST) differs by type of living arrangement and cognitive ability of the person with dementia. Next, a value of information analysis is performed to inform decisions about future research. Methods: Incremental cost-effectiveness analysis applying seemingly unrelated regressions using data from a multicentre RCT of MCST versus treatment as usual in a population which had already received 7 weeks of CST for dementia (ISRCTN: 26286067). The findings from the cost-effectiveness analysis are used to inform a value of information analysis. Results: The results are dependent upon how quality adjusted life years (QALYs) are measured. MCST might be cost-effective compared to standard treatment for those who live alone and those with higher levels of cognitive functioning. If a further RCT was to be conducted for this sub-group of the population, value of information analysis suggests a total sample of 48 complete cases for both sub-groups would be required for a two-arm trial. The expected net gain of conducting this future research is £920 million. Conclusion: Preliminary results suggest that MCST may be most cost-efficient for people with dementia who live alone and/or who have higher cognition. Future research in this area is needed.

Keywords: cognitive functioning; cost-effectiveness; expected value of sample information; Maintenance cognitive simulation therapy; residency (search for similar items in EconPapers)
JEL-codes: E6 (search for similar items in EconPapers)
Pages: 6 pages
Date: 2019-05-04
New Economics Papers: this item is included in nep-mac
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Citations: View citations in EconPapers (1)

Published in Aging and Mental Health, 4, May, 2019, 23(5), pp. 602-607. ISSN: 1360-7863

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